Design of a randomized trial to determine the optimum protein intake to preserve lean body mass and to optimize response to a promyogenic anabolic agent in older men with physical functional limitation.

Research Program in Men's Health: Aging and Metabolism, Boston Claude D. Pepper Older Americans Independence Center for Function Promoting Therapies, Brigham and Women's Hospital, United States. Electronic address: sbhasin@partners.org. Section of Endocrinology, Diabetes and Nutrition, Boston Medical Center, United States. Institute for Aging Research, Hebrew SeniorLife, Division of Gerontology, Beth Israel Deaconess Medical Center, United States. Research Program in Men's Health: Aging and Metabolism, Boston Claude D. Pepper Older Americans Independence Center for Function Promoting Therapies, Brigham and Women's Hospital, United States. Section of Preventive Medicine and Epidemiology, Boston Medical Center, Boston, MA, United States. Department of Nutrition Science, Purdue University, West Lafayette, IN, United States.

Contemporary clinical trials. 2017;:86-93

Abstract

The dietary protein allowance for older men to maintain lean body mass and muscle strength and to accrue optimal anabolic responses to promyogenic stimuli is poorly characterized. The OPTIMEN trial was designed to assess in older men with moderate physical dysfunction and insufficient habitual protein intake (

Methodological quality

Publication Type : Randomized Controlled Trial

Metadata